Difference between revisions of "Acrylamide"
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| − | Acrylamide is a known neurotoxin and carcinogen. Its industrially produced for various purposes (eg | + | Acrylamide is a known neurotoxin and carcinogen. Its industrially produced for various purposes (eg polymeres). Amides are derivates of ammonia or (carboxylated) amines. In cooked food, acrylamide may be yielded by the reaction of amino acids and carbonyls or simple sugars. Environmentally, it may be the result of decomposition of polyacrylamide (in herbicides) |
| − | Acrylamide decomposes in the presence of acids, bases and oxidizing agents, rendering ammonia or nitrogen oxides. | + | Acrylamide decomposes in the presence of acids, bases and oxidizing agents, rendering ammonia or nitrogen oxides. Endogenously, acrylamide is metabolized to glycidamide (an expoxide). |
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A food additive, AF-2,2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, was first demonstrated to be mutagenic in Escherichia coli WP-2 and then proved to be carcinogenic in experimental animals. [http://www.ncbi.nlm.nih.gov/pubmed/7341982] | A food additive, AF-2,2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, was first demonstrated to be mutagenic in Escherichia coli WP-2 and then proved to be carcinogenic in experimental animals. [http://www.ncbi.nlm.nih.gov/pubmed/7341982] | ||
Revision as of 14:50, 24 November 2012
Acrylamide is a known neurotoxin and carcinogen. Its industrially produced for various purposes (eg polymeres). Amides are derivates of ammonia or (carboxylated) amines. In cooked food, acrylamide may be yielded by the reaction of amino acids and carbonyls or simple sugars. Environmentally, it may be the result of decomposition of polyacrylamide (in herbicides) Acrylamide decomposes in the presence of acids, bases and oxidizing agents, rendering ammonia or nitrogen oxides. Endogenously, acrylamide is metabolized to glycidamide (an expoxide).
A food additive, AF-2,2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, was first demonstrated to be mutagenic in Escherichia coli WP-2 and then proved to be carcinogenic in experimental animals. [1]
